Dimethyl Sulfoxide (DMSO) is a naturally occurring organic sulfur compound, originally derived as a byproduct from wood pulp processing. It is known for its exceptional ability to penetrate skin and biological membranes, delivering rapid relief from pain and inflammation.

How DMSO Works in the Body

DMSO does not rely on receptor-mediated pathways for entry into the body. Instead, it passes through cell membranes via passive diffusion. This means it crosses biological barriers based on its molecular structure and solubility characteristics, not by docking with cell surface receptors.

Transport Capabilities

One of DMSO’s most unique features is its ability to carry other compounds across the skin and into the bloodstream. It can dissolve both polar and non-polar substances, meaning it can transport water-soluble and fat-soluble molecules alike. This makes it an effective carrier of nutrients—or toxins—if the application area is not clean or the compound mixed with it is unsafe.

Key Benefits of DMSO

Anti-inflammatory and analgesic properties

Antioxidant activity and cellular protection

Enhanced circulation and tissue oxygenation

Useful in injury recovery, arthritis, and nerve-related pain

Cautions and Considerations

Because DMSO is a powerful carrier, it's essential to use only pharmaceutical-grade DMSO

Use on clean, unbroken skin.

It should not be combined with unknown or harmful substances, and should always be handled with clean hands and tools.

It can warm up upon application, this is common and not of concern, if it becomes too warm, dilute with organic oil or aloe.